School of Life Sciences (SLS): Recent submissions

Now showing items 241-260 of 365

EFFECT OF Garcinia kola EXTRACTS ON MONOSODIUM GLUTAMATE-INDUCED ORGAN TOXICITY IN RATS

KAREEM, AKEEM (Federal University Of Technology, Akure., 2018-10)

Monosodium glutamate (MSG) is a major flavour enhancer extensively used as a food additive. Despite its taste stimulation and appetite enhancement, many studies have linked MSG to several pathological and biochemical ...
ALTERED REDOX HOMEOSTASIS AND OXIDATION OF ESSENTIAL THIOLS ASSOCIATED WITH LEAD-MEDIATED DYSFUNCTION OF SYNAPTOSOMAL ELECTROGENIC SODIUM PUMP.

ADENEYE, MODUPE ADEDAYO (Federal University Of Technology, Akure., 2016-04)

The biochemical and molecular events associated with lead (Pb2+)-induced neuronal dysfunction is complex and multifactorial. The present study evaluated the in vitro and in vivo interaction of lead with the synaptosomal ...
IN-VITRO INHIBITORY EFFECT OF TURMERIC RHIZOME (Curcuma longa) EXTRACT AND FRACTIONS ON THE BIOACTIVITY OF ANGIOTENSIN-1 CONVERTING ENZYME

ABIORO, OBAFEMI OLAWUMI (Federal University Of Technology, Akure., 2016-04)

Angiotensin-1 converting enzyme (ACE-1), is a key component the renin angiotensin aldosterone system (RAAS), which regulates blood pressure. Since the over expression of RAAS is known to be associated with vascular ...
EFFECT OF MORINGA (Moringa oleifera) LEAF EXTRACT ON THE ANTIHYPERTENSIVE PROPERTY OF LISINOPRIL

OYETOMI, OYEWUMI JOHN (Federal University Of Technology, Akure., 2015-05)

Angiotensin-I Converting Enzyme (ACE) inhibitors are the common drugs used in the management of hypertension and they are mostly combined with traditional therapies in Nigeria. However, there is dearth of information on ...
EFFECTS OF KOLAVIRON ON NEUROLOGICAL DEFICIT AND BRAIN REDOX HOMEOSTASIS IN RATS SUBJECTED TO GLOBAL ISCHEMIA/REPERFUSION

OLOWOOKERE, BOYEDE DELE (Federal University Of Technology, Akure., 2015-06)

This study was designed to investigate the protective potential of kolaviron against global ischemia/reperfusion-induced brain damage in male Wistar rats. Animals which were 48 in number were divided into eight groups with ...
ANTIPLASMODIAL ACTIVITY OF THE EXTRACT OF ASTHMA WEED (EUPHORBIA HIRTA) AGAINST PLASMODIUM BERGHEI BERGHEI IN INFECTED MICE

JEJE, TEMITOPE OLAWALE (Federal University Of Technology, Akure., 2014-12)

Malaria is a mosquito borne infectious disease of humans and other animals caused by parasitic protozoans (a type of unicellular microorganism) of the genus plasmodium. It affects a large number of the world’s population. ...
PURIFICATION AND CHARACTERIZATION OF PHYTASE FROM Bacillus licheniformis PFBL- 03

FASIMOYE, FEYISOLA OPEYEMI (Federal University Of Technology, Akure., 2013-04)

Phytase from Bacillus licheniformis PFBL-03 was purified in three steps by using ammonium sulphate precipitation, ion exchange chromatography on DEAE Sephadex A-50 and gel filtration chromatography on Sephadex G-100. The ...
EXTRACTION, PURIFICATION AND CHARACTERIZATION OF POLYPHENOL, OXIDASE FROM SNAKE GOURD (Trichosanthes cucumerina)

DABESOR, PETER ANANI (Federal University Of Technology, Akure., 2015-06)

Polyphenol oxidases (PPOs) are enzymes that catalyze the oxidation of a wide range of phenolic compound by utilizing molecular oxygen. Polyphenol oxidase from Snake gourd (Trichosanthes cucumerina) was purified to homogeneity ...
INFLUENCE OF THIOL ON REACTION MECHANISM SWITCHING OF ORGANOSELENIUM IN in vitro MODELS OF OXIDATIVE STRESS

BALOGUN, BOSEDE DAMILOLA (Federal University Of Technology, Akure., 2014-12)

The antioxidant mechanism of action of organoseleniums in rat’s brain is largely linked with either their glutathione peroxidase (GPx) or peroxiredoxin mimetic activities. However, the precise molecular dynamics between ...
ACETAMINOPHEN-INDUCED LIVER DAMAGE IN ALBINO RATS: EFFECTS OF PARINARI FLAVONOIDS ON SOME BIOCHEMICAL INDICES AND ANTIOXIDANT DEFENCE SYSTEM

AMOBONYE, Ayodeji Emmanuel (Federal University Of Technology, Akure., 2014-12)

The present study investigated the hepatoprotective potential of flavonoid-rich fraction (FRE) of Parinari curatellifolia Planch (Chrysobalanceae) in experimental rats with a view to ascertain the validity of folkloric ...
Antioxidant Activities, Nutritional Potential and Physico-chemical Analysis of Unripe plantain-Millet Composite flour blend

SHAIBU, RAMOTU (Federal University of Technology, Akure, 2014-12)

The functional properties of plant foods had received much attention in recent times. However, several investigations have revealed the antioxidant, nutritional and medicinal potential of unripe plantain and millet when ...
Partial Purification and Characterization of Alkaline Protease from Bacillus brevis Isolated from Milk Processing Waste Site

FALADE, MATHEW AYODELE (Federal University of Technology, Akure, 2013-04)

Fifteen alkalophilic Bacillus species isolated from six different waste sites were evaluatedin respect to proteolytic activity on casein agar. Bacillus brevis isolated from milk processing waste site exhibited the highest ...
BIOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF AFRICAN STAR APPLE (Chrysophyllum albidum Linn) LEAF EXTRACT IN GENTAMICIN-INDUCED HEPATO-RENAL DYSFUNCTIONS IN RATS

DARAMOLA, OMOBOLA MUYIWA (Federal University of Technology, Akure, 2021-04)

Hepatic and renal dysfunctions are now major health challenges with attendant high mortality, morbidity and economic cost. Treatment with orthodox medicines have undesirable side effects necessitating the quest for alternative ...
ANTIOXIDANT POTENTIAL OF PHENOLICS IN TWO LOCAL VARIETIES OF RICE AND THEIR ANTICHOLINESTERASE ACTIVITIES AFTER IN VITRO DIGESTION

ALAO, ODUNAYO FUNMILOLA (Federal University Of Technology, Akure., 2015-05)

Rice is an important staple food crop for human health because it provides the bulk of calories for more than half of the world’s population. Rice crops are rich in polyphenols that are responsible for lowering the risk ...
POSSIBLE INVOLVEMENT OF HYDROPHILIC THIOLS OF LACTATE DEHYDROGENASE ON THE GLUTATHIONE PEROXIDASE-LIKE CATALYTIC MECHANISM OF DIPHENYL DISELENIDE.

AJAYI, BUNMI OLAOLUWA (Federal University of Technology, Akure, 2015-06)

The antioxidant mechanism of action of diphenyl diselenide, an organoselenium, is largely linked with its glutathione peroxidase (GPx) activity. However, the precise relationship between the GPx-mimicry of diphenyl diselenide ...
ANTIOXIDANT POTENTIAL AND INHIBITORY EFFECT OF IN VITRO DIGESTED SPECIES OF BITTER YAM (Dioscorea dumetorum) ON CHOLINESTERASE AND LIPID PEROXIDATION

AJIBOYE, BLESSING PRAISE (Federal University Of Technology, Akure, 2015-06)

Ample studies have related the health promoting properties of most plant foods to their phytochemical constituents as well as their antioxidant properties. Bitter yam (Dioscorea dumetorum) has been reported to be rich ...
PRODUCTION OF POLYCLONAL ANTI-HUMAN HEMOGLOBIN A, C, F AND S ANTIBODY IN RABBIT

AJAYI, olawale david (Federal University of Technology, Akure, 2014-02)

Polyclonal antibodies represent a group of mixture of antibodies produced by different B-lymphocytes in response to the same antigen. Thus, different antibodies in the group recognize different parts of the antigen. ...
ANTIOXIDANT PROPERTY OF AFRICAN MANGO SEED (IRVINGIA GABONENSIS) AND ITS MODULATORY EFFECT ON THE LIPID PROFILE OF ALBINO RAT

ADEOLU, TAIWO OLUWATOSIN (Federal University of Technology, Akure, 2012-11)

In this study, the antioxidant property of Irvingia gabonesis seed and its effect on the serum lipids of albino rats were evaluated. Phytochemical screening and proximate composition analysis of I. gabonensis seed were ...
BIOCHEMICAL, HEMATOLOGICAL AND GROWTH INDICES OF HIV – POSITIVE PATIENTS ON HAART AT THE FEDERAL MEDICAL CENTRE (FMC), OWO, NIGERIA.

ADEMUYIWA, SUCCESS EUNICE ADEYINKA (Federal University Of Technology, Akure., 2013-05)

Selected biochemical and haematological indices were determined in Human Immunodeficiency Virus (HIV) – infected patients that were on HAART at the Federal Medical Centre (FMC), Owo, Nigeria. A total of one hundred and ...
INFLUENCE OF GALLIC AND TANNIC ACIDS ON THE ANTIOXIDANT, ALPHA AMYLASE AND ALPHA GLUCOSIDASE INHIBITORY PROPERTIES OF ACARBOSE

ADEGBOLA, DEBORAH OLAYINKA (Federal University Of Technology, Akure., 2017-01)

In this study, gallic acid (GA) and its octa-polymeric form- tannic acid (TA), which are two phenolic acids abundantly found in plant foods such as vegetables, fruits and legumes, were investigated for their influence on ...

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